US 4,994,033 AGranted

Intravascular drug delivery dilatation catheter

AssigneeSchneider (USA) Inc.

InventorsRick L. Shockey, Robert A. Van Tassel

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Abstract

An intravascular catheter designed to apply a liquid medicament or other substance to a stenotic lesion as the blood vessel is undergoing dilatation to facilitate the restoration and long-term maintenance of patency to the blood vessel. It comprises three concentrically arranged flexible plastic tubes and a pair of concentrically arranged expander members located at the distal end of the tubes. The space between the outer wall of the inner tube and the inner wall of the intermediate tube is in fluid communication with the interior of the first expander member while the space between the outer wall of the intermediate tube and the inner wall of the outer tube is in fluid communication with the interior of the second expander member. A plurality of minute holes are formed through the second expander member such that when the liquid medicament is introduced into the lumen of the outer tube while an inflation fluid is introduced into the lumen of the intermediate tube, both expander members inflate with the drug or other substance being ejected out through the tiny pores of the outermost expander member while continued inflation of the inner expander member provides the necessary pressure for dilatation of the lesion.

Claims8

Dependent claims

An intravascular material delivery dilatation catheter comprising:

first, second and third elongated, flexible, hollow, plastic tubular members of descending diameter concentrically disposed relative to one another and each having a proximal end, a distal end and defining a lumen extending between the proximal end and the distal end, the distal end of the third tubular member extending beyond the distal ends of the first and second tubular members:
inner hollow expansible sleeve means bonded at one end to the third tubular member near the distal end thereof and at the other end to the distal end of the second tubular member, the interior of the inner hollow expansible sleeve means further being in fluid communication with the portion of the lumen defined by the second tubular member outside the third tubular member;
outer hollow expansible membrane sleeve means bonded at one end near the distal end of the third tubular member and at the other end to the distal end of the first tubular member, the interior of the outer hollow sleeve means further being in fluid communication with the portion of the lumen of the first tubular member defined between the first and second tubular members, the outer hollow sleeve means including a pattern of minute openings extending radially therethrough;
and
manifold means connected to the proximal ends of the first and second tubular members for introducing an inflation fluid into the lumen of the second tubular member outside the third tubular member and a liquid dispersant into the lumen of the first tubular member outside the second tubular member whereby an amount of dispersant can be caused to perfuse through the minute openings in the outer sleeve means as the inner hollow sleeve means is expanded by the inflation fluid.

2 more elements

A method for treating an atherosclerotic lesion on the interior wall of a blood vessel comprising the steps of:

providing a dilatation catheter comprising
first, second and third elongated, flexible, hollow plastic tubular members concentrically disposed relative to one another and each having a proximal end, a distal end defining a lumen extending between the proximal end and the distal end;
inner hollow expander membrane sleeve bonded at one end to the third tubular member near the distal end thereof and at the other end to the distal end of the second tubular member, the interior of the inner hollow expander defined by the sleeve being in fluid communication with the lumen of said second tubular member outside the third tubular member;
outer hollow expander membrane sleeve bonded at one end near the distal end of the third tubular member and at the other end to the distal end of the first tubular member, the interior of the outer hollow expander sleeve being in fluid communication with the lumen defined between the first and second tubular members, the outer hollow expander sleeve including a pattern of minute openings extending radially therethrough;
and
manifold means connected to the proximal ends of the first and second tubular members for introducing an inflation fluid into the lumen of the second tubular member and a liquid medicament into the lumen of the first tubular member in a manner whereby the medicament can perfuse through the openings in the outer expander sleeve as the inner sleeve expands;
routing the dilatation catheter through the patient's vascular system until the expander sleeves are juxtaposed relative to the lesion;
inflating the inner expander member to apply pressure against said lesion;
and
simultaneously perfusing a dispersant through the outer expander member and onto the lesion.

7 more elements

Dependencies are inferred from the claim text.