Inhibitors of slow reacting substance of anaphylaxis
AssigneeSchering Corporation
InventorsAnil K. Saksena, Jesse K. Wong, Pietro Mangiaracina
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Abstract
Novel compounds and compositions which inhibit SRS-A in mammals are disclosed. Methods for preparing said compounds and compositions and methods for their use for treating allergic reactions, inflammation and for reducing the severity of myocardial infarction resulting from heart attack are disclosed. Useful intermediates for preparing said compounds are also disclosed.
Claims6
A compound having the structural formula ##STR7## or a pharmaceutically acceptable salt thereof formed with ammonia, an organic amine or an alkali metal base, where T is alkyl of from 8 to 13 carbon atoms;
- and x and x.sup.1 are straight chain alkylene having 2 or 3 carbon atoms.
A compound having, the name:
- 1-propane, 3,3'-[(2-pentadecynuylidene)bis(thio)]-bis-carboxylic acid.
Dependencies are inferred from the claim text.