Optically active benzene derivatives and process for preparation thereof
AssigneeSumitomo Chemical Company, Limited
InventorsMasayoshi Minai, Takayuki Higashi
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Abstract
Disclosed are novel optically active benzene derivatives represented by the formula (I): ##STR1## wherein R represents an alkyl or alkoxyalkyl group having 1 to 20 carbon atoms, which group may contain a halogen; Z represents a hydrogen atom or a halogen atom; l and n each represents a number of 0 or 1; and * indicates asymmetric carbon atom, and a process for preparing the above optically active benzene derivative which comprises debenzylating an optically active benzyl derivative represented by the formula (II): ##STR2## wherein, R, Z, l, n and * have the same meanings as defined above, and A represents a hydrogen atom, a lower alkyl group, a lower alkoxyl group or a halogen atom.
Claims39
Optically active benzene derivatives represented by the formula (I):
- ##STR21## wherein R represents an alkyl or alkoxyalkyl group having 1 to 20 carbon atoms, which group may contain a halogen;
- Z represents a hydrogen atom or a halogen atom;
- l and n each represents a number of 0 or 1;
- and * indicates asymmetric carbon atom.
The process according to claim 26, wherein the microorganism is the one belonging to the genus Pseudomonas or Arthrobacter.
An optically active benzyl derivative represented by the formula (II):
- ##STR27## wherein A represents a hydrogen atom, a lower alkyl group, a lower alkoxyl group or a halogen atom;
- R represents an alkyl or alkoxyalkyl group having I to 20 carbon atoms, which group may contain a halogen;
- Z represents a hydrogen atom or a halogen atom;
- l and n each represents a number of 0 to 1;
- and * indicates asymmetric carbon atom.
An optically active alcohol represented by the formula (III):
- ##STR28## wherein A represents a hydrogen atom, a lower alkyl group, a lower alkoxyl group or a halogen atom;
- Z represents a hydrogen atom or a halogen atom;
- l represents a number of 0 or 1;
- and * indicates asymmetric carbon atom.
Dependencies are inferred from the claim text.