Pharmaceutical formulations for parenteral use
AssigneeUniversity of Florida
InventorNicholas S. Bodor
Life of this patent
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Abstract
Aqueous parenteral solutions of drugs which are insoluble or only sparingly soluble in water and/or which are unstable in water, combined with hydroxypropyl-.beta.-cyclodextrin, provide a means for alleviating problems associated with drug precipitation at the injection site and/or in the lungs or other organs following parenteral administration.
Claims41
A method for decreasing the incidence of precipitation of a lipophilic and/or water-labile drug occurring at or near the injection site and/or in the lungs or other organs following parenteral administration, said method comprising parenterally administering said drug in an aqueous solution containing from about 20% to about 50% hydroxypropyl-.beta.-cyclodextrin.
Dependencies are inferred from the claim text.