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US 4,968,826 AGranted
Platinum complexes and antitumor agents containing them as an active ingredient
AssigneeShionogi & Co., Ltd.
InventorsTetsushi Totani, Osamu Shiratori, Yoshihiro Muraoka
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Abstract
Novel platinum complexes of the formula: ##STR1## wherein R.sup.1 and R.sup.2 each identically of differently is lower alkyl, or R.sup.1 and R.sup.2 taken together form --(CH.sub.2)m--, and m is an integer from 2 to 5, and antitumor agents comprising the compound (I), which are effective against cisplatin-resistant ascitic murine leukemia, murine leukemia, and solid tumor, with slight hemotoxicity and nephrotoxicity.
Claims10
A compound of the formula:
- ##STR12## wherein R.sup.1 and R.sup.2 each identically or differently is lower alkyl, or R.sup.1 and R.sup.2 taken together form --(CH.sub.2)m--, and m is an integer from 2 to 5.
Dependencies are inferred from the claim text.