In a guide wire for use in measuring a characteristic of liquid flow in a vessel, a flexible elongate tubular element having proximal and distal extremities, a core wire extending through at least a portion of the flexible elongate tubular element and having a tapered distal extremity extending beyond the distal extremity of the tubular element, a coil extending over and beyond the distal extremity of the core wire, the coil having a proximal extremity and a distal extremity, means securing the proximal extremity of the coil to the distal extremity of the tubular element, transducer means secured to the distal extremity of the coil, first and second conductor means carried by the tubular element and connected to the transducer and extending to the proximal extremity of the tubular element, means bonding the tubular element and the coil to the core wire so that torsional forces applied to the tubular element are supplied to the coil and protective means associated with the coil and the tubular element for preventing liquid in the vessel from coming into contact with the first and second conductor means extending through the coil and the tubular element.