A device for establishing esophagoenterostomies, comprising a hollow housing (1), an outer sleeve (2) and an inner sleeve (3) interconnected telescopically and communicating with the hollow housing, the inner sleeve (3) being extended from the outer one (2) to form an area adapted to mount an elastic ring (6), which compresses the biological tissues being joined together during anastomosis formation, each of said sleeves having an opening (4, 5) in the bottom thereof, through which the respective sleeve (2, 3) communicated with the hollow housing (1), a bushing (7) accommodated in one of the organs (9) to be anastomosed and having a first annular groove (11) on its outside surface for anastomosis formation by means of the elastic ring (6), and a probe (14) connected to the bushing (7) and passing through the interior spaces of the bushing (7), sleeves (2, 3) and hollow housing (1), characterized in that it incorporates a second bushing (8) having an annular groove (13) on its outside surface for securing thereon the end of the other organ (10) being anastomosed, while the first bushing (7) has a second annular groove (12) on its outside surface, adapted to secure the end of the first organ (9) being anastomosed, said first bushing resting upon a shoulder (16) made in the probe (1 4), which makes it possible, during anastomosis formation, to join the bushings (7, 8) together into a single unit, to put them inside the sleeves (2, 3) and, while moving the inner sleeve (3), to throw the elastic ring (6) off from the outside surface of the inner sleeve (3) in order to compress the organs (9, 10) being anastomosed in the first annular groove (11) of the first bushing (7), all the motions mentioned above being actuated by virtue of the probe travel.