Photo-inactivation of cancer cells
AssigneeRowland Institute for Science
InventorsJames W. Foley, Louis Cincotta
Life of this patent
Estimating the term…
Abstract
A compound having the formula ##STR1## in which X is O, S, or Se; each R.sub.1, R.sub.2, and R.sub.3, independently, is H, a lower alkyl, or aralkyl; A is a saturated or unsaturated ring; and each Z.sub.1, Z.sub.2, Z.sub.3, Z.sub.4, Z.sub.5, Z.sub.6, Z.sub.7, or Z.sub.8, independently, is H or a halogen, provided that when X is O, at least one group Z is a halogen; when either Z.sub.2 or Z.sub.3 is a halogen, at least one of R.sub.2 or R.sub.3 is H; and when both Z.sub.2 and Z.sub.3 are halogens, both R.sub.2 and R.sub.3 are H; or a pharmaceutically acceptable salt thereof. The compounds are useful for photo-inactivation of cancer cells.
Claims13
A compound having the formula ##STR15## wherein X is O, S, or Se;
- each R.sub.1, R.sub.2, and R.sub.3, independently, is H, lower alkyl, or aralkyl;
- ring A is a saturated or unsaturated ring;
- and each Z.sub.1, Z.sub.2, Z.sub.3, Z.sub.4, Z.sub.5, Z.sub.6, Z.sub.7, and Z.sub.8, independently, is H or a halogen,
- provided that when X is 0, at least one group Z is a halogen;
- when either Z.sub.2 or Z.sub.3 is a halogen, at least one of R.sub.2 or R.sub.3 is H;
- and when both Z.sub.2 and Z.sub.3 are halogens, both R.sub.2 and R.sub.3 are H;
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.