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US 4,960,710 AGranted
Device and method of assaying for trace mounts of proteins
AssigneeMiles Inc.
InventorArthur L. Lau
Life of this patent
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AssigneeMiles Inc.
InventorArthur L. Lau
Estimating the term…
A new and improved method and composition for determining the presence and concentration of low to trace amounts of proteins, such as albumin, in a test sample, such as urine. The method includes using a reagent composition capable of interacting with low to trace amounts of proteins to produce a visually or instrumentally detectable and/or measurable response. The method can be used in wet assays or in dry test strip assays, wherein the reagent composition is incorporating into a carrier matrix. The new and improved reagent composition, comprising a dye, such as a polyhydroxybenzenesulfonephthalein-type indicator, like pyrocatechol violet; a tungstate, such as ammonium tungstate; and, if necessary, a suitable buffer, is incorporated into the carrier matrix to provide sufficient sensitivity to low to trace protein levels and sufficient color resolution between low to trace protein levels, thereby affording an accurate and trustworthy protein assay of test samples having a low protein concentration.
A method of detecting and/or differentiating concentrations of protein in a liquid sample at protein concentration levels in the range of 0-2000 mg/dL;
A method of detecting and/or differentiating concentrations of protein in a liquid sample at protein concentration levels in the range of 0-2000 mg/dL:
An analyte detection device to determine the presence and/or concentration of protein in a liquid test sample at protein concentration levels in the range of 0-2000 mg/dL comprising:
A method of detecting and measuring low to trace amounts of protein at levels of 30 mg/dL or less in a liquid sample comprising:
Dependencies are inferred from the claim text.