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US 4,952,512 AGranted
Gene encoding an inhibitor of tissue-type and urokinase-type plasminogen activators
OwnerDavid J. Loskutoff, Tor Ny +1inventors
InventorsDavid J. Loskutoff, Tor Ny, Michael Sawdey
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Abstract
A biological reagent and diagnostic system for the detection and quantitation of endothelial plasminogen activator inhibitor (PAI) are disclosed, as are substantially pure, recombinant human endothelial PAI, its biologically pure gene and a vector for cloning the gene and expressing a gene product.
Claims10
A biologically pure DNA molecule encoding human endothelial plasminogen activator inhibitor that is from about 1140 to about 3000 nucleotides in length that comprises the nucleotide sequence of FIG. 22 from nucleotide position 13 to about position 1153.
Dependencies are inferred from the claim text.