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US 4,950,672 AGranted
2-substituted-8.alpha.-branched chain acylaminoergolines
AssigneeSandoz Ltd.
InventorWalter Haefliger
Life of this patent
Estimating the term…
Abstract
Compounds of the formula I ##STR1## wherein R.sub.1 is hydrogen or C.sub.1-4 alkyl, R.sub.2 is hydrogen, chlorine, bromine or methyl, R.sub.3 is C.sub.1-5 alkyl or C.sub.3-5 alkenyl and R.sub.4 is C.sub.3-7 alkyl; C.sub.3-7 cycloalkyl; adamantyl; or optionally substituted phenyl, having valuable pharmaceutical, and in particular LH- and PRL-secretion inhibiting as well as neuroleptic activity.
Claims7
A compound of formula I ##STR31## wherein R.sub.1 is hydrogen,
- R.sub.2 is chlorine, bromine or methyl,
- R.sub.3 is methyl, and
- R.sub.4 is branched chain C.sub.3-7 alkyl, or an acid addition salt thereof.
Dependencies are inferred from the claim text.