Method for transporting substances into living cells and tissues and apparatus therefor
AssigneeCornell Research Foundation, Inc.
InventorsJohn C. Sanford, Edward D. Wolf, Nelson K. Allen
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Abstract
Inert or biologically active particles are propelled at cells at a speed whereby the particles penetrate the surface of the cells and become incorporated into the interior of the cells. The process can be used to mark cells or tissue or to biochemically affect tissues or tissue in situ as well as single cells in vitro. Apparatus for propelling the particles toward target cells or tissues are also disclosed. A method for releasing particles adhered to a rotor device is also disclosed.
Claims22
A method for introducing particles into cells comprising accelerating particles having a diameter sufficiently small to penetrate and be retained in a preselected cell without killing the cell, and propelling said particles at said cells whereby said particles penetrate the surface of said cells and become incorporated into the interior of said cells.
Dependencies are inferred from the claim text.