Method for inhibiting post-surgical adhesion formation by the topical administration of non-steroidal anti-inflammatory drug
AssigneeEthicon, Inc.
InventorsWarren D. Sheffield, Douglas B. Johns, Shalaby W. Shalaby, Gere S. diZerega, LeRoy L. Richer
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Abstract
Postsurgical adhesion formation is inhibited by the topical administration to the site of surgical trauma of a non-steroidal anti-inflammatory drug, preferably ibuprofen, suprofen, or tolmetin.
Claims24
A process for inhibiting post-surgical adhesion formation in mammals which comprises the topical locally effective administration to the injured tissue surface site of surgical trauma of an effective amount of a composition including as an active ingredient a non-steroidal anti-inflammatory drug, such administration beginning after surgery and continuing for a period of time sufficient to inhibit the formation of post-surgical adhesions.
A sterile aqueous composition including a surface active agent and a non-steroidal anti-inflammatory drug.
A sterile composition comprising an absorbable polymer microcapsule containing a non-steroidal anti-inflammatory drug.
A sterile composition comprising an aqueous composition containing hyaluronic acid or pharmaceutically acceptable salt or ester thereof and a non-steroidal anti-inflammatory drug or pharmaceutically acceptable salt or ester thereof.
Dependencies are inferred from the claim text.