Metal-based antimicrobial coating
AssigneeBioInterface Technologies, Inc.
InventorChristopher C. Capelli
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Abstract
A medical device with an antimicrobial coating that is safe, effective, photostable and readily manufacturable can be produced by applying a composition to at least one body fluid-contacting surface of the device such that a solid coating is provided on that surface, the coating composition comprising an oligodynamic metal salt of a sulfonylurea, a polymeric material, at least one acid compound selected from the group consisting of a water-soluble carboxylic acid and water-insoluble carboxylic acid, and a carrier liquid in which foregoing components are soluble. The antimicrobial coating accommodates variation in the release of antimicrobial metal ions as a function of the intended use for a medical device to which the coating is applied.
Claims9
A medical device comprising (a) a substrate presenting a surface suitable for contact with a body fluid and (b) an antimicrobial coating provided on said surface, said coating comprising an oligodynamic metal salt of a sulfonylurea, a polymeric material and at least one acid compound selected from the group consisting of a water-soluble carboxylic acid and a water-insoluble carboxylic acid, said device being suitable for extended contact with a body, of a patient or with body fluids.
The device of claim wherein said polymeric material comprises polyurethane, polyvinylchloride, nylon, polystyrene, polyethylene, polyvinyl alcohol, polyvinyl acetate, silicone and polyester.
The device of claim -, wherein said water-insoluble carboxylic acid comprises stearic acid, capric acid, lauric acid, myristic acid, palmitic acid, arachidic acid, cholic acid, deoxycholic acid, taurocholic acid or glycocholic acid.
Dependencies are inferred from the claim text.