Back to results
US 4,919,939 AGranted
Periodontal disease treatment system
AssigneePharmetrix Corporation
InventorRichard W. Baker
Life of this patent
Estimating the term…
Abstract
A controlled release drug delivery system for placement in the periodontal pocket, gingival sulcus, tooth socket, wound or other cavity within the mouth. The system incorporates drug-containing microparticles in a fluid carrier medium, and is effective in the environment of use for up to 30 days.
Claims47
A controlled drug delivery system for placement in a periodontal pocket, comprising:
- (a) a plurality of discrete microparticles, between 10 and 500 microns in diameter, comprising a drug and a polymer containing said drug, wherein when said microparticles are placed in an environment of use, said drug is released at a controlled rate by a combination of diffusion of said drug through said polymer and erosion of said polymer;
- and
- (b) a fluid suspending medium for said microparticles;
- said drug delivery system remaining active in the periodontal pocket for a period of between one and thirty days.
1 more element
A controlled drug delivery system for placement in a periodontal pocket, comprising:
- (a) a plurality of discrete microparticles, between 10 and 500 microns in diameter, comprising a drug and a polymer containing said drug, said drug being essentially insoluble in said polymer, wherein when said microparticles are placed in an environment of use, said drug is released at a controlled rate by erosion of said polymer;
- and
- (b) a fluid suspending medium for said microparticles;
- said drug delivery system remaining active in the periodontal pocket for a period of between one and thirty days.
1 more element
A controlled drug delivery system for placement in a periodontal pocket, comprising:
- (a) a plurality of discrete microparticles, between 10 and 500 microns in diameter, comprising at least 15 vol % drug dispersed in a polymer, said drug being essentially insoluble in said polymer, wherein when said microparticles are placed in an environment of use, said drug is released at a controlled rate by leaching of said drug from said polymer;
- and
- (b) a fluid suspending medium for said microparticles;
- said drug delivery system remaining active in the periodontal pocket for a period of between one and thirty days.
1 more element
Dependencies are inferred from the claim text.