Method of preparing cyclodextrin-coated surfaces
AssigneeUop LLC
InventorRonald P. Rohrbach
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Abstract
Polyisocyanate crosslinked cyclodextrin resins prepared within a certain mole ratio of polyisocyanate to cyclodextrin are soluble in solvents such as pyridine and dimethylformamide but highly insoluble in water. Such resins have excellent adhesive properties toward virtually all solid surfaces which consequently can be readily coated with a thin film having a multiplicity of cyclodextrin moieties available at the surface for separation and/or purification. Such coated substrates can be prepared in a variety of sizes, shapes, and cyclodextrin loading quite conveniently and relatively inexpensive.
Claims33
A method of coating a solid phase substrate with a polyisocyanate crosslinked cyclodextrin resin comprising contacting a solution of the polyisocyanate crosslinked cyclodextrin resin in a dipolar aprotic solvent with said substrate to afford a wetted substrate, removing the solvent from said wetted substrate to give the substrate coated with the polyisocyanate crosslinked cyclodextrin resin, and recovering the coated substrate, where the polyisocyanate crosslinked cyclodextrin resin is the reaction product of a cyclodextrin with a polyisocyanate in a molar proportion effective to afford said product with a water solubility less than about 200 ppm and with a solubility in at least one dipolar aprotic solvent of at least 0.1 weight percent.
A solid phase substrate coated with a polyisocyanate crosslinked cyclodextrin resin comprising a solid phase substrate selected from the group consisting of ceramics, glass, plastics, metals, fabrics, and cellulosic products having a coating of from about 0.1 to about 10.0 weight percent based on the finished product of a polyisocyanate crosslinked cyclodextrin resin, said resin being the reaction product of a cyclodextrin with a polyisocyanate in a molar proportion effective to afford said product with a water solubility less than about 200 ppm and with a solubility in at least one dipolar aprotic solvent of at least 0.1 weight percent.
Dependencies are inferred from the claim text.