Printed transdermal drug delivery device
AssigneeCygnus Research Corporation
InventorsJesus Miranda, Gary W. Cleary
Life of this patent
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Abstract
A method for making transdermal drug delivery devices is provided which includes: laminating an adsorbent source layer to a pressure-sensitive, pharmaceutically acceptable contact adhesive; depositing a drug in liquid form on one face of the source layer; laminating an anchor adhesive layer to the opposing face of the source layer; and applying a drug-impermeable backing layer to the anchor adhesive, which backing layer then defines the upper surface of the device. The invention also encompasses transdermal drug delivery devices having a source layer in contact with and contained between anchor and contact adhesive layers, with a backing layer adjacent the anchor adhesive defining the upper surface of the device.
Claims12
A method for making a transdermal delivery device, comprising:
- (a) laminating an adsorbent source layer to a pressure-sensitive, pharmaceutically acceptable contact adhesive layer, the contact adhesive layer comprised of a material that is permeable to the drug and which defines a basal surface for adhesion to skin;
- (b) printing a drug in liquid form onto the adsorbent fabric layer;
- (c) laminating an anchor adhesive layer to the source layer;
- and
- (d) applying a backing layer to the anchor adhesive layer which defines the upper surface of the device and is substantially impermeable to the drug.
A method for making a transdermal delivery device comprising:
- (a) laminating an adsorbent fabric layer to a pressure-sensitive, pharmaceutically acceptable contact adhesive layer, the contact adhesive layer comprised of a material that is permeable to the drug and which defines a basal surface for adhesion to skin;
- (b) printing an enhancer onto the adsorbent fabric layer;
- (c) laminating an anchor adhesive layer to the fabric layer;
- and
- (d) applying a backing layer to the anchor adhesive layer which defines the upper surface of the device and is substantially impermeable to the drug,
- wherein prior to said laminating, the drug is incorporated into the anchor adhesive layer, the contact adhesive layer, or both.
A method for making a fragrance-releasing device, comprising:
- (a) laminating an adsorbent fabric layer, adapted to initially retain a fragrance in liquid form, to a pressure-sensitive, pharmaceutically acceptable contact adhesive layer which defines a basal surface;
- (b) printing a fragrance in liquid form onto the adsorbent fabric layer, whereby the fragrance is incorporated and initially retained therein;
- (c) laminating an anchor adhesive layer to the fabric layer, the anchor adhesive layer comprised of a material that is substantially pormeable to the fragrance;
- and
- (d) applying a backing layer to the anchor adhesive layer which defines the upper surface of the device and is substantially permeable to the fragrance.
Dependencies are inferred from the claim text.