Hinged dermal applicator

A device for applying an active agent carrier to the skin or mucosa of a patient comprising a liner layer including a first surface and a second surface, said first surface of said liner layer comprising a releasable surface, a carrier layer for said active agent carrier, said carrier layer including a first surface and a second surface, said active agent carrier being located on said first surface of said carrier layer, first adhesive means interposed between said first surface of said carrier layer and said active agent carrier for maintaining said active agent carrier in contact with said carrier layer when said carrier layer is separated from said liner layer, and second adhesive means interposed between said first surface of said liner layer and said first surface of said carrier layer including said active agent carrier, for releasably maintaining said first surface of said carrier layer including said active agent carrier in contact with said first surface of said liner layer, said second adhesive means covering at least the entire periphery of said active agent carrier, said first adhesive means having a first coefficient of adhesion and said second adhesive layer having a second coefficient of adhesion, said first coefficient of adhesion of said carrier layer to said active agent carrier being less than said second coefficient of adhesion of said active agent carrier to said skin or mucosa of said patient, whereby upon application of said active agent carrier to said skin or mucosa of said patient with said second adhesive means therebetween, said active agent carrier adheres to said skin or mucosa of said patient and said active agent carrier can thereby be removed from said carrier layer.

A device for applying an active agent carrier to the skin or mucosa of a patient comprising a liner layer including a first surface and a second surface, said first surface of said liner layer comprising a releasable surface, a carrier layer for said active agent carrier, said carrier layer including a first surface and a second surface, hinge means permanently affixing said first surface of said liner layer to said first surface of said carrier layer at a predetermined location thereon, said active agent carrier being located on said first surface of said carrier layer at a location displaced from said hinge means, first adhesive means interposed between said first surface of said carrier layer and said active agent carrier for maintaining said active agent carrier in contact with said carrier layer when said portion of said carrier layer other than said hinge means is separated from said liner layer, and second adhesive means interposed between said first surface of said liner layer and said first surface of said carrier layer including said active agent carrier, for releasably maintaining said first surface of said carrier layer including said active agent carrier in contact with said first surface of said liner layer, said second adhesive means covering at least the entire periphery of said active agent carrier, said first adhesive means having a first coefficient of adhesion and said second adhesive layer having a second coefficient of adhesion, said first coefficient of adhesion of said carrier layer to said active agent carrier being less than said second coefficient of adhesion of said active agent carrier to said skin or mucosa of said patient, whereby upon application of said active agent carrier to said skin or mucosa of said patient with said second adhesive means therebetween, said active agent carrier adheres to said skin or mucosa of said patient and said active agent carrier can thereby be removed from said carrier layer.

A device for applying a film layer and an active agent carrier to the skin or mucosa of a patient comprising a liner layer including a first surface and a second surface, said first surface of said liner layer comprising a releasable surface, a carrier layer for said film layer and said active agent carrier, said carrier layer including a first surface and a second surface, said film layer including a first surface and a second surface, said first surface of said film layer being located on said first surface of said carrier layer, a first adhesive layer interposed between said first surface of said carrier layer and said first surface of said film layer for maintaining said film layer in contact with said carrier layer when said carrier layer is separated from said liner layer, said active agent carrier being located on said second surface of said film layer, and a second adhesive layer interposed between said first surface of said liner layer and said first surface of said carrier layer including said film layer and said active agent carrier, for releasably maintaining said first surface of said carrier layer including said film layer and said active agent carrier in contact with said first surface of said liner layer, said second adhesive layer covering at least the entire periphery of said film layer, said first adhesive layer having a first coefficient of adhesion and said second adhesive layer having a second coefficient of adhesion, said first coefficient of adhesion of said carrier layer to said film layer being less than said second coefficient of adhesion of said film layer to said skin or mucosa of said patient, whereby upon application of said film layer and said active, agent carrier to said skin or mucosa of said patient with said second adhesive layer therebetween, said film layer and said active agent carrier adhere to said skin or mucosa of said patient and said film layer and said active agent carrier can be simultaneously removed from said carrier layer.

A device for applying a film layer and an active agent carrier to the skin or mucosa of a patient comprising a liner layer including a first surface and a second surface, said first surface of said liner layer comprising a releasable surface, a carrier layer for said film layer and said active agent carrier, said carrier layer including a first surface and a second surface, hinge means permanently affixing said first surface of said liner layer to said first surface of said carrier layer at a predetermined location thereon, said film layer including a first surface and a second surface, said first surface of said film layer being located on said first surface of said carrier layer at a location displaced from said hinge means, a first adhesive layer interposed between said first surface of said carrier layer and said first surface of said film layer for maintaining said film layer in contact with said carrier layer when said portion of said carrier layer other than said hinge means is separated from said liner layer, said active agent carrier being located on said second surface of said film layer, and a second adhesive layer interposed between said first surface of said liner layer and said first surface of said carrier layer including said film layer and said active agent carrier, for releasably maintaining said first surface of said carrier layer including said film layer and said active agent carrier in contact with said first surface of said liner layer, said second adhesive layer covering at least the entire periphery of said film layer, said first adhesive layer having a first coefficient of adhesion and said second adhesive layer having a second coefficient of adhesion, said first coefficient of adhesion of said carrier layer to said film layer being less than said second coefficient of adhesion of said film layer to said skin or mucosa of said patient, whereby upon application of said film layer and said active agent carrier to said skin or mucosa of said patient with said second adhesive layer therebetween, said film layer and said active agent carrier adhere to said skin or mucosa of said patient and said film layer and said active agent carrier can be simultaneously removed from aid carrier layer.

A device for applying a film layer to the skin or mucosa of a patient comprising a liner layer including a first surface and a second surface, said first surface of said liner layer comprising a releasable surface, a carrier layer for said film layer, said carrier layer including a first surface and a second surface, said liner layer and said film layer having corresponding outer peripheries, said film layer being located on said first surface of said carrier layer, temporary closure means for temporarily sealing said first surface of said liner layer to said first surface of said carrier layer at at least a portion of the corresponding outer peripheries thereof so as to provide a sealed container for said film layer therein, said temporary closure means comprising a peelable heat seal formed between said first surface of said liner layer and said first surface of said carrier layer, a first adhesive layer interposed between said first surface of said carrier layer and said film layer for maintaining said film layer in contact with said carrier layer when said temporary closure means is unsealed and said carrier layer is separated from said liner layer, and a second adhesive layer interposed between said first surface of said liner layer and said first surface of said carrier layer including said film layer for releasably maintaining said first surface of said carrier layer including said film layer in contact with said first surface of said film layer in contact with said first surface of said liner layer, said second adhesive layer covering at least the entire periphery of said film layer, said first adhesive layer having a first coefficient of adhesion and said second adhesive layer having a second coefficient of adhesion, said first coefficient of adhesion of said carrier layer to said film layer being less than said second coefficient of adhesion of said film layer to said skin or mucosa of said patient, whereby upon application of said film layer to said skin or mucosa of said patient with said second adhesive layer therebetween, said film layer adheres to said skin or mucosa of said patient and said film layer can simultaneously be removed from said carrier layer.

A device for applying a film layer to the skin or mucosa of a patient comprising a liner layer including a first surface and a second surface, said first surface of said liner layer comprising a releasable surface, a carrier layer for said film layer, said carrier layer including a first surface and a second surface, said liner layer and said film layer having corresponding outer peripheries, hinge means permanently affixing said first surface of said liner layer to said first surface of said carrier layer at a predetermined location comprising a portion of said corresponding outer peripheries thereof, said film layer being located on said first surface of said carrier layer at a location displaced from said hinge means, temporary closure means for temporarily sealing said first surface of said liner layer to said first surface of said carrier layer at the remaining portion of said corresponding outer peripheries thereof so as to provide a sealed container for said film layer therein, a first adhesive layer interposed between said first surface of said carrier layer and said film layer for maintaining said film layer in contact with said carrier layer when said temporary closure means is unsealed and said portion of said carrier layer other than said hinge means is separated from said liner layer, and a second adhesive layer interposed between said first surface of said liner layer and said first surface of said carrier layer including said film layer for releasably maintaining said first surface of said carrier layer including said film layer in contact with said first surface of said film layer in contact with said first surface of said liner layer, said second adhesive layer covering at least the entire periphery of said film layer, said first adhesive layer having a first coefficient of adhesion and said second adhesive layer having a second coefficient of adhesion, said first coefficient of adhesion of said carrier layer to said film layer being less than said second coefficient of adhesion of said film layer to said skin or mucosa of said patient, whereby upon application of said film layer to said skin or mucosa of said patient with said second adhesive layer therebetween, said film layer adheres to said skin or mucosa of said patient and said film layer can simultaneously be removed from said carrier layer.

A device for applying a film layer and an active agent carrier to the skin or mucosa of a patient comprising a liner layer including a first surface and a second surface, said first surface of said liner layer comprising a releasable surface, a carrier layer for said film layer and said active agent carrier, said carrier layer including a first surface and a second surface, said liner layer and said film layer having corresponding outer peripheries, said film layer including a first surface and a second surface, and said first surface of said film layer being located on said first surface of said carrier layer, temporary closure means for temporarily sealing said first surface of said liner layer to said first surface of said liner layer to said first surface of said carrier layer at at least a portion of said corresponding outer peripheries thereof, so as to provide a sealed container for said film layer and said active agent carrier therein, a first adhesive layer interposed between said first surface of said carrier layer and said first surface of said film layer for maintaining said film layer in contact with said carrier layer when said temporary closure means is unsealed and said portion of said carrier layer other than said hinge means is separated from said liner layer, and a second adhesive layer interposed between said first surface of said liner layer and said first surface of said carrier layer including said film layer and said active agent carrier for releasably maintaining said first surface of said carrier layer including said film layer and said active agent carrier in contact with said first surface of said liner layer, said second adhesive layer covering at least the entire periphery of said film layer, said first adhesive layer having a first coefficient of adhesion and said second adhesive layer having a second coefficient of adhesion, said first coefficient of adhesion of said carrier layer to said film layer being less than said second coefficient of adhesion of said film layer to said skin or mucosa of said patient, whereby upon application of said film layer and said active agent carrier to said skin or mucosa of said patient with said second adhesive layer therebetween, said film layer and said active agent carrier adhere to said skin or mucosa of said patient and said film layer and said active agent carrier can simultaneously be removed from said carrier layer.

A device for applying a film layer and an active agent carrier to the skin or mucosa of a patient comprising a liner layer including a first surface and a second surface, said first surface of said liner layer comprising a releasable surface, a carrier layer for said film layer and said active agent carrier, said carrier layer including a first surface and a second surface, said liner layer and said film layer having corresponding outer peripheries, hinge means permanently affixing said first surface of said liner layer to said first surface of said carrier layer at a predetermined location comprising a portion of said corresponding outer peripheries thereof, said film layer including a first surface and a second surface, and said first surface of said film layer being located on said first surface of said carrier layer at a location displaced from said hinge means, temporary closure means for temporarily sealing said first surface of said liner layer to said first surface of said liner layer to said first surface of said carrier layer at the remaining portion of said corresponding outer peripheries thereof, so as to provide a sealed container for said film layer and said active agent carrier therein, a first adhesive layer interposed between said first surface of said carrier layer and said first surface of said film layer for maintaining said film layer in contact with said carrier layer when said temporary closure means is unsealed and said portion of said carrier layer other than said hinge means is separated from said liner layer, and a second adhesive layer interposed between said first surface of said liner layer and said first surface of said carrier layer including said film layer and said active agent carrier for releasably maintaining said first surface of said carrier layer including said film layer and said active agent carrier in contact with said first surface of said liner layer, said second adhesive layer covering at least the entire periphery of said film layer, said first adhesive layer having a first coefficient of adhesion and said second adhesive layer having a second coefficient of adhesion, said first coefficient of adhesion of said carrier layer to said film layer being less than said second coefficient of adhesion of said film layer to said skin or mucosa of said patient, whereby upon application of said film layer and said active agent carrier to said skin or mucosa of said patient with said second adhesive layer therebetween, said film layer and said active agent carrier adhere to said skin or mucosa of said patient and said film layer and said active agent carrier can simultaneously be removed from said carrier layer.