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US 4,913,152 AGranted
Magnetoencephalograph (MEG) using a multi-axis magnetic gradiometer for localization and tracking of neuromagnetic signals
AssigneeThe Johns Hopkins University
InventorsHarvey W. Ko, Joseph P. Skura, Harry A. C. Eaton
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Abstract
An apparatus and method for the passive, non-invasive magnetoencephalographic (MEG) localization and tracking of sources of magnetic signals in the brain is disclosed. The apparatus and method uses a multi-axis magnetic gradiometer to detect the magnetic field, field gradient, and polarization emanating from neuronal sources in the brain under either normal or pathological conditions.
Claims7
A method for locating sources of magnetic signals emanating from a patient, comprising the steps of:
- positioning a first bundle of at least three single-axis magnetometers near a patient with the magnetometers oriented to measure the same vector component (z) of the biomagnetic field but with the magnetometers laterally displaced from each other;
- differencing signals obtained from sets of two magnetometers to calculate lateral spatial gradients of the measured biomagnetic field;
- and,
- calculating a two-dimensional location for the source of the biomagnetic field by analyzing the lateral spatial gradients.
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