Process for preparing .alpha.-substituted carbonyl compound
AssigneeAgency of Industrial Science and Technology
InventorsMasato Tanaka, Toshiyasu Sakakura
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Abstract
A process is disclosed for the preparation of .alpha.-substituted carbonyl compounds, wherein .alpha.-substituted ketone is prepared by the following reaction: ##STR1## .alpha.-azo ester is prepared by the following reaction: ##STR2## and .alpha.-hydrozono ester is prepared by the following reaction: ##STR3## wherein the .alpha.-azo ester and .alpha.-hydrazono ester obtained by the above reactions include novel compounds, which are also disclosed.
Claims6
A process for the preparation of an .alpha.-hydrazono ester represented by the formula ( 7), which comprises reacting a ketene silyl acetal represented by the formula (6) with a diazonium salt represented by the formula (2):
- ##STR61## ##STR62## wherein R.sup.1 is a member selected from the group consisting of C.sub.1-8 alkyl, C.sub.7-8 aralkyl, C.sub.6-10 aryl, C.sub.2-8 alkenyl, C.sub.2-8 alkynyl, C.sub.3-5 heteroaryl and substituted derivatives thereof containing a substituent selected from the group consisting of halogen, alkoxy, alkoxycarbonyl, dialkylamino, .beta.-indolyl, dialkoxymethyl, thioalkoxy, nitro and cyano;
- each of R.sup.2, R.sup.3, R.sup.4 and R.sup.8 is a member independently selected from the group consisting of the above alkyl, aryl and aralkyl;
- R.sup.5 is a member selected from the group consisting of phenyl, chlorophenyl, bromophenyl, nitrophenyl, tolyl, anisyl, formylphenyl, ethoxycarbonylphenyl, dimethoxymethylphenyl, naphthyl, pyridyl, furyl, thienyl and 4,4'-biphenylenyl;
- and X is a member selected from the group consisting of Cl, HSO.sub.4, NO.sub.3, ClO.sub.4, BF.sub.4, B(C.sub.6 H.sub.5).sub.4, PF.sub.6, CH.sub.3 CO.sub.2, 1/2 ZnCl.sub.4, 1/2 SnCl.sub.6, 1/2 HgCl.sub.4, 1/2 CdCl.sub.4, 1/3 Fe(CN).sub.6 and FeCl.sub.4.
Dependencies are inferred from the claim text.