Use of 1,4-disubstituted-piperidinyl compounds in the manufacture of a medicament for the treatment of insomnia
AssigneeMerrell Dow Pharmaceuticals Inc.
InventorsPaul J. Schechter, John M. Orwin, Christian K. Hinze
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Abstract
The present invention pertains to the use of 1,4-disubstituted-piperidinyl compounds in the treatment of insomnia. Said compounds have the following general formula: ##STR1## wherein: each of R.sup.1, R.sup.2, R.sup.3, and R.sup.4 is independently selected from the group consisting of hydrogen, a C.sub.1-6 alkyl group, halogen, trifluoromethyl, hydroxy, a C.sub.1-6 alkoxy group, or an amino group; n is 2, 3, or 4; and the pharmaceutically acceptable acid addition salts thereof.
Claims20
A method for the treatment of insomnia comprising administering to a patient suffering from insomnia, a hypnotic quantity of a compound of the formula:
- ##STR3## wherein n is 2, 3, or 4, each of R.sup.1, R.sup.2, and R.sup.4 is independently selected from hydrogen, halogen, trifluoromethyl, C.sub.1-6 alkyl, C.sub.1-16 alkoxy, hydroxy or amino;
- or a pharmaceutically acceptable acid addition salt thereof.
Dependencies are inferred from the claim text.