Tetrahydroisoquino(2,1-C)(1,3)benzodiazepines
AssigneeHoechst-Roussel Incorporated
InventorsLawrence L. Martin, Richard C. Allen
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Abstract
Novel Tetrahydroisoquino[2,1-c][1,3]benzodiazepines are disclosed having the formula ##STR1## where X and Y are each independently hydrogen, halogen, loweralkyl, loweralkoxy or --CF.sub.3, and R is hydrogen or loweralkyl, and the pharmaceutically acceptable acid addition salts thereof and where applicable the geometric and optical isomers and racemic mixtures thereof. The compounds of this invention display utility in enhancing memory.
Claims11
A compound of the formula ##STR11## where X and Y are independently hydrogen, halogen, loweralkyl, loweralkoxy or --CF.sub.3 and R is hydrogen or loweralkyl;
- and the pharmaceutically acceptable acid addition salts thereof and where applicable the optical isomers and racemic mixtures thereof.
A memory enhancing composition which comprises an effective memory enhancing amount of a compound of the formula ##STR12## where X and Y are independently hydrogen, halogen, loweralkyl, loweralkoxy or --CF.sub.3 and R is hydrogen or loweralkyl;
- and the pharmaceutically acceptable acid addition salts thereof and where applicable the optical isomers and racemic mixtures thereof, and a pharmaceutically acceptable carrier thereof.
A method of enhancing the memory of an mammal in need of such enhancement which comprises administering to a mammal a memory enhancing amount of a compound having the formula ##STR13## where X and Y are independently hydrogen, halogen, loweralkyl, loweralkoxy or --CF.sub.3 and R is hydrogen or loweralkyl;
- and the pharmaceutically acceptable acid addition salts thereof and where applicable the geometric and optical isomers and racemic mixtures thereof.
Dependencies are inferred from the claim text.