Skin treatment method
AssigneeDow Corning Corporation
InventorsRichard L. Gettings, William C. White
Life of this patent
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Abstract
A method of treating skin disorders such as acne vulgaris by applying topically to the epidermis a composition of an emulsion in which there is present a silane and a volatile low viscosity low molecular weight water immiscible liquid of a silicone fluid, causing the silane to penetrate follicular orifices, using the volatile silicone fluid for the purpose of driving the silane into sebaceous glands, and destroying members of the staphylococcal group of bacteria therein. An abrasive, astringent, and fragrance may also be included. This method also allows for the treatment of dermatosis, such as ring worm and athlete's foot.
Claims7
A method of treating acne vulgaris comprising applying topically to the epidermis a mixture of an antibacterially effective amount of a silane and a water immiscible liquid, the silane being an organosilicon quaternary ammonium compound and an organosilane having the formula selected from the group consisting of ##STR8## wherein, in each formula, Y is R or RO where each R is an alkyl radical of 1 to 4 carbon atoms or hydrogen;
- a has a value of 0, 1 or 2;
- R' is a methyl or ethyl radical;
- R" is an alkylene group of 1 to 4 carbon atoms;
- R'", R"" and R.sup.v are each independently selected from a group consisting of alkyl radicals of 1 to 18 carbon atoms, --CH.sub.2 C.sub.6 H.sub.5, --CH.sub.2 CH.sub.2 OH, --CH.sub.2 OH, and --(CH.sub.2).sub.x NHC(O)R.sup.vi, wherein x has a value of from 2 to 10 and R.sup.vi is a perfluoroalkyl radical having from 1 to 12 carbon atoms;
- and
- X is chloride, bromide, fluoride, iodide, acetate or tosylate, the water immiscible liquid being a polysiloxane having the formula (R'R"SiO).sub.y wherein R' is an alkyl radical of 1 to 3 carbon atoms;
- R" is an alkyl radical of 1 or 2 carbon atoms;
- and y has a value of 3 to 5.
Dependencies are inferred from the claim text.