Silicon semiconductor wafer for analyzing micronic biological samples
AssigneeE. I. Du Pont de Nemours and Company
InventorSalvatore J. Pace
Life of this patent
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Abstract
An analytical separation device in which a capillary sized conduit is formed by a channel in a semiconductor device and the channel is closed by a glass plate. Electrodes are positioned in the channel and to activate the motion of liquids through the conduit by electroosmosis.
Claims23
An improved separation device, comprising a capillary sized, closed conduit adapted to be filled with liquid or solid materials for electrophoretic and/or chromatographic separations, means to introduce a sample to be processed into the conduit, the device characterized by
- a semiconductor slab having a channel in one face and a cover plate attached to the one slab to form the closed conduit, adapted to receive an ionizable liquid, and means for applying an electric potential along the length of the interior of the conduit.
An improved gel electrophoresis device with a first conduit having an inlet and an outlet, the conduit being filled with an electrophoretic gel, means for applying an electric potential along the length of the interior of the conduit inlet, and a detector positioned along the conduit, the device characterized by
- all dimensions transverse to the conduit being greater than 100 .mu.m, and
- the conduit being defined by a silicon slab having a channel in one face and a cover plate attached to the one slab face to form the conduit.
Dependencies are inferred from the claim text.