Pharmaceutical composition for the treatment of periodontal disease
AssigneeRohto Pharmaceutical Co., Ltd.
InventorsKiyotsugu Higashi, Shigeru Kametaka, Reiko Izumi, Katsuhiko Morisaki, Shin'ichi Hayashi
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Abstract
A pharmaceutical composition useful for treatment of periodontal diseases which comprises one or more active ingredients effective for the treatment of periodontal diseases, characterized in that said active ingredient or ingredients are dispersed in collagen.
Claims11
In the art of applying active ingredients useful for the treatment of periodontal disease dispersed in collagen in order to protect against increased collagenase activity which always accompanies progression of periodontal disease, directly to the periodontal pocket, the improvement consisting of the step of placing in said periodontal pocket an extruded bar, film or ointment of periodontal agent dispersed in glutaraldehyde cross-linked succinylated atelocollagen gel in a 1 to 9 ratio with hydroxypropylcellulose.
Dependencies are inferred from the claim text.