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US 4,906,668 AGranted
Aminoalkyl phenyl selenides for the treatment of hypertension and nervous system dysfunctions
AssigneeGeorgia Tech Research Corporation
InventorsSheldon W. May, Heath H. Herman, Steven F. Roberts
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Abstract
The preparation of aminoalkyl phenyl selenides and pharmaceutically acceptable salts thereof is disclosed which are useful for the treatment of hypertension and related vascular diseases and the treatment of nervous system dysfunctions.
Claims4
A method of treating nervous system dysfunctions in mammals comprising administering to the mammal an amount of an aminoalkyl phenyl selenide effective to modulate adronergic neuronal activity in the mammal, said aminoalkyl phenyl selenide having the formula:
- ##STR2## wherein:
- R.sub.1 -R.sub.5 =H, OH, C.sub.1 -C.sub.4 -alkoxy, C.sub.1 -C.sub.4 -alkyl, F, Cl, Br, I;
- R.sub.6, R.sub.7 =H, C.sub.1 -C.sub.4 alkyl;
- and
- (CHx).sub.n = any straight or branched, saturated or unsaturated carbon chain wherein n=1 to 10 and x=0, 1 or 2;
- and pharmaceutically acceptable addition salts thereof.
3 more elements
Dependencies are inferred from the claim text.