Pharmaceutical compositions containing saturated aromatic peroxides
AssigneeL'oreal
InventorsBernard Jacquet, Michel Hocquaux, Didier Semeria, Didier Saint-Leger
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Abstract
A pharmaceutical or cosmetic composition contains as an active principle a peroxide having an aromatic radical and a saturated group and having the formula ##STR1## wherein R.sub.1 represents linear or branched alkyl having 3 to 17 carbon atoms, substituted or not by one or more halogens, interrupted or not by a carbonyl group and carrying a terminal carboxylic acid group esterified or not or R.sub.1 represents cycloalkyl having 5 to 10 carbon atoms, and R.sub.2 represents hydrogen, halogen, --CF.sub.3, methoxy, ethoxy or acyl having 2 to 16 carbon atoms. The composition is usefully employed in the treatment of various dermatoses including acne.
Claims13
An anti-acne composition having improved keratolytic activity for application to the skin comprising, in a pharmaceutically or cosmetically acceptable and topically applicable carrier, as an active principle, at least one peroxide having an aromatic radical and a saturated group and having the formula ##STR3## wherein R.sub.1 represents linear or branched alkyl having 3 to 17 carbon atoms substituted or not by one or more halogens, interrupted or not by carbonyl and having a terminal carboxylic acid group esterified or not, or R.sub.1 represents cycloalkyl having 5 to 10 carbon atoms, and
- R.sub.2 represents hydrogen, halogen, --CF.sub.3, methoxy, ethoxy, or acyl having 2 to 16 carbon atoms,
- said peroxide being present in an amount ranging from 0.1 to 20 weight percent based on the total weight of said composition.
Dependencies are inferred from the claim text.