Method of treating posttraumatic nervous injuries with dipeptide derivatives
AssigneeGruenenthal GmbH
InventorsHubert Giertz, Hans Barth, Leopold Flohe
Life of this patent
Estimating the term…
Loading patent…
AssigneeGruenenthal GmbH
InventorsHubert Giertz, Hans Barth, Leopold Flohe
Estimating the term…
A method of preventing or treating posttraumatic nervous injuries by administering a compound of the formula: ##STR1## wherein R.sub.1 is hydrogen, a lower alkyl group, cyclohexyl or benzyl; Z is one of the groups ##STR2## if Z is a group (a), R.sub.2 and R.sub.3 together represent an additional bond between the carbon atoms bearing them, or if Z represents a group (b), R.sub.2 is hydrogen; R.sub.4 is hydrogen or lower alkyl; R.sub.5 is hydrogen, lower alkyl or phenyl, and R.sub.6 is hydrogen or methyl. Hydrates or pharmaceutically acceptable acid addition salts may also be used in the method. Pharmaceutical compositions used in this method containing such compounds in a prophylactically or therapeutically effective amount may be administered by infusion, injection, orally, perorally, rectally, percutaneously or other route.
A method of preventing or treating posttraumatic nervous injuries comprising administering to a patient suffering from traumata of the spinal cord or of the brain an effective nervous injury affecting amount of a compound corresponding to the formula:
Dependencies are inferred from the claim text.