Biodegradable poly(hydroxyalkyl)amino dicarboxylic acid) derivatives, a process for their preparation, and the use thereof for depot formulations with controlled delivery of active ingredient
AssigneeHoechst Aktiengesellschaft
InventorsHubert Bader, Diether Ruppel, Axel Walch
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Abstract
The invention relates to biodegradable poly((hydroxyalkyl)amino dicarboxylic acid) derivatives of the formula I ##STR1## in which n, m, x, y, z, R and R' have the indicated meanings, and to a process for their preparation and to the use thereof for depot formulations with controlled delivery of active ingredient.
Claims4
Poly((hydroxyalkyl)amino dicarboxylic acid) derivatives of the formula I ##STR6## in which n is 1 or 2, m is 2 to 6, x and y are 1 to 400, and z is 0 to 40, and in which the radicals R and R' are identical or, independently of one another, different and denote branched or unbranched, saturated or unsaturated alkyl, cycloalkyl, alkoxy or cycloalkyloxy groups having a total of 1-22 carbon atoms in the alkyl moiety, it being possible for the alkyl moiety optionally to be interrupted by a carbonyloxy group, or biologically inactive steroid alcohols bonded via their hydroxyl groups, there being random distribution in the polymer of the monomer units placed in square brackets.
Dependencies are inferred from the claim text.