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US 4,904,816 AGranted
Process for the manufacture of anilinofumarate via chloromaleate or chlorofumarate or mixtures thereof
AssigneeAmerican Cyanamid Company
InventorsAlbert A. Cevasco, Donald Roy
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Abstract
There is provided a novel process for the manufacture of anilinofumarate via chloromaleate or chlorofumarate or mixtures thereof.
Claims8
A method for the preparation of anilinofumarate of formula I ##STR7## wherein R is C.sub.1 -C.sub.4 alkyl which comprises reacting chloromaleate of formula II or chlorofumarate of formula III or mixtures thereof ##STR8## wherein R is C.sub.1 -C.sub.4 alkyl with about 1.0 to 1.5 molar equivalents of aniline in the presence of about 1.0 to 1.8 molar equivalents of aqueous base containing a phase transfer catalyst to form the anilinofumarate.
Dependencies are inferred from the claim text.