D-cycloserine and its prodrugs as cognitive enhancers
AssigneeG. D. Searle & Co.
InventorsAlex A. Cordi, Gail E. Handelmann, Joseph B. Monahan
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Abstract
The compound D-4-amino-3-isoxazolidone, its pharmaceutically-acceptable salts and its prodrug compounds are described as having cognitive-enhancing activity.
Claims6
A composition for use in improvement or enhancement of memory, said composition comprising a memory enhancing therapeutically-effective amount of D-4-amino-3-isoxazolidone or a pharmaceutically-acceptable salt thereof.
A composition comprising a therapeutically-effective amount of D-4-amino-3-isoxazolidone or a pharmaceutically acceptable salt thereof, said amount being effective to treat a cognitive deficit linked to a neurological disorder.
A method to improve or enhance memory comprising administering to an animal a therapeutically-effective amount of a compound selected from the group consisting of 4-amino-3-isoxazolidone and a pharmaceutically-acceptable salt thereof.
A method to treat a cognitive deficit linked to a neurological disorder comprising administering a therapeutically effective amount of a compound of the group consisting of 4-amino-3-isoxazolidone and a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.