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US 4,904,676 AGranted
Amino-oxazole compounds having dopaminergic activity
AssigneeAkzo N.V.
InventorsDuncan R. Rae, Samuel G. Gibson
Life of this patent
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Abstract
The present invention relates to new amino-thiazole and amino-oxazole derivatives of the general formula: ##STR1## wherein: R represents hydrogen, a lower alkyl group with 1 to 4 carbon atoms, a lower alkenyl group, a phenyl-alkyl (1-4 C), furanyl-alkyl (1-4 C) or thienyl-alkyl (1.varies.4 C) group; X represents sulphur or oxygen; R.sub.1 and R.sub.2 represent hydrogen or alkyl (1-4 C), and the dotted line represents an optional extra bond, as well as pharmaceutically acceptable acid addition salts thereof, having potent dopamine-agonist activity.
Claims4
Amino-oxazole derivatives of the formula:
- ##STR6## wherein:
- R represents hydrogen;
- X represents oxygen;
- R.sub.1 and R.sub.2 represent hydrogen or alkyl (1-4 C), and the dotted line represents an optional extra bond, as well as pharmaceutically acceptable acid addition salts thereof.
1 more element
Dependencies are inferred from the claim text.