Agent for treating bradycardia and bradyarrhythmia
AssigneeDr. Karl Thomae GmbH
InventorsWolfgang Eberlein, Wolfhard Engel, Gerhard Mihm, Norbert Mayer, Adriaan de Jonge
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Abstract
(.+-.)-1-[4-[Ethyl[2-(4-methoxyphenyl)-1-methylethyl]-amino]-1-oxobutyl]-N, N-dimethyl-4-piperidine carboxamide and (+)-1-[4-[ethyl[2-(4-methoxyphenyl)-1-methylethyl]-amino]-1-oxobutyl]N,N-d imethyl-4-piperidinecarboxamide, as well as the physiologically acceptable acid addition salts of these compounds are suitable for the treatment of bradycardia and bradyarrhythmia.
Claims2
A method for treatment of bradycardia in a warm-blooded animal comprising administering to said animal a therapeutically effective amount of a compound selected from the group consisting of (.+-.)-1-[4-[ethyl[2-(4-methoxyphenyl)-1-methylethyl]amino]-1-oxobutyl]-N, N-dimethyl-4-piperidinecarboxamide, and (+)-1-[4-[ethyl[2-(4-methoxyphenyl)-1-methylethyl]amino]-1-oxobutyl]-N,N-d imethyl-4-piperidinecarboxamide or physiologically acceptable salts of these compounds with inorganic or organic acids.
A method for treatment of bradyarrhythmia in a warm-blooded animal comprising administering to said animal to therapeutically effective amount of a compound selected from the group consisting of (.+-.)-1-[4-[ethyl[2-(4-methoxyphenyl)-1-methylethyl]amino]-1-oxobutyl]-N, N-dimethyl-4-piperidinecarboxamide, and (+)-1-[4-[ethyl[2-(4-methoxyphenyl)-1-methylethyl]amino]-1-oxobutyl]-N,N-d imethyl-4-piperidinecarboxamide or physiologically acceptable salts of these compounds with inorganic or organic acids.
Dependencies are inferred from the claim text.