Method for producing L-sorbose
AssigneeTakeda Chemical Industries, Ltd.
InventorsIkuo Nogami, Hideo Shirafuji, Takamasa Yamaguchi, Masahide Oka
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Abstract
L-sorbose, an intermediate important in vitamin C synthesis, is produced in higher yield from D-sorbitol by microbiological oxidation using a microorganism which belongs to the genus Gluconobacter and which has decreased ability to grow with D-sorbitol as the single carbon source compared with that of its parent strains.
Claims5
A process for producing L-sorbose, which comprises oxidizing D-sorbitol microbiologically using a mutant microorganism selected from the group consisting of Gluconobacter suboxydans BL-9 (FERM BP-1241), Gluconobacter suboxydans BL-115 (FERM BP-1240), Gluconobacter oxydans GO-10 (FERM BP-1169) and Gluconobacter oxydans GO-14 (FERM BP-1170), said mutant microorganism having a degree of growth in minimum media containing D-sorbitol as the single carbon source which is less than 1/10 of said degree of growth of the parent strain of said mutant microorganism.
A microorganism selected from the group consisting of Gluconobacter suboxydans BL-9 (FERM BP-1241), Gluconobacter suboxydans BL-115 (FERM BP-1240), Gluconobacter oxydans GO-10 (FERM BP-1169) and Gluconobacter oxydans GO-14 (FERM BP-1170), said microorganism having a degree of growth in minimum media containing D-sorbitol as the single carbon source which is less than 1/10 of said degree of growth of the parent strain of said microorganism.
A biologically pure culture of a microorganism belonging to the genus Gluconobacter having characteristics identifiable with those of a member selected from the group consisting of FERM BP-1241, FERM BP-1240, FERM BP-1169 and FERM BP-1170, said culture oxidizing D-sorbitol to L-sorbose in a culture medium containing assimilable carbon and digestable nitrogen sources, said microorganism having a degree of growth in minimum media containing D-sorbitol as the single carbon source which is less than 1/10 of said degree of growth of the parent strain of said microorganism.
Dependencies are inferred from the claim text.