Spray dried ibuprofen compositions
AssigneeAmerican Home Products Corporation
InventorsYing T. R. Ho, Robert G. Blank
Life of this patent
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Abstract
A spray dried ibuprofen composition suitable for direct compression into tablets comprising a spray dried dispersion in water of ibuprofen, pregalatinized starch, a disintegrant and a wetting agent for the ibuprofen.
Claims7
A spray dried ibuprofen composition in powder form suitable for direct compression into tablets consisting essentially of about 80% to about 90% by weight ibuprofen, about 2% to about 6% by weight of a disintegrant selected from the class consisting of crospovidone, croscarmellose sodium and sodium starch glycolate, about 8% to about 12% by weight pregelatinized starch, and about 0.2% to about 2% by weight of a wetting agent selected from the class consisting of polyvinylpyrrolidone and sodium lauryl sulfate, the powder having been spray dried from a dispersion in water of the ibuprofen, the disintegrant, the gelatinized starch and the wetting agent.
Dependencies are inferred from the claim text.