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US 4,904,462 AGranted
Multiply-tritiated steroidal-20,17-spirolactones and their use as tracer compounds
AssigneeSchering Corporation
InventorsPaul-Eberhard Schulze, Klaus Nickisch, Henry Laurent, Kunhard Pollow
Life of this patent
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Abstract
Novel, multiple-tritiated steroid-20,17-spirolactones of general Formula I ##STR1## wherein --A--B-- is --CH.sub.2 --CH.sub.2 --, --CH.dbd.CH-- or ##STR2## and --C--D-- is ##STR3## R is hydrogen or tritium and n is 0 or 1, are usable as tracer materials for the detection of mineralocorticoid receptors.
Claims13
A multiple-tritiated steroid-20,17-spirolactone of the formula ##STR14## wherein --A--B-- is --CH.sub.2 --CH.sub.2 --, --CH.dbd.CH-- or ##STR15## and --C--D-- is ##STR16## R is hydrogen or tritium and n is 0 or 1,
- with the proviso that at least three R-groups are tritium.
Dependencies are inferred from the claim text.