Ammine-alicyclic amine-platinum complexes and antitumor agents
AssigneeShionogi & Co., Ltd.
InventorsTetsushi Totani, Katsutoshi Aono, Yasuko Adachi
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Abstract
A compound of the formula (I): ##STR1## (wherein R is C.sub.1 -C.sub.6 alkyl, hydroxy, carboxy, C.sub.1 -C.sub.6 alkoxy, halogen or oxo; m is an integer from 2 to 7; X and Y each is chlorine or nit-rato ligand, or taken together form --OCOCH(R.sup.1)O--, OCOCOO--, ##STR2## R.sup.1 is hydrogen, C.sub.1 -C.sub.5 alkyl, hydroxymethyl, halogmethyl or phenyl; R.sup.2 is hydrogen or C.sub.1 -C.sub.5 alkyl; and n is an integer from 2 to 5), being useful as antitumor agents is provided.
Claims2
A compound which is (ammine)(glyccolato-O,O')(pyrrolidine)platinum (II).
A compound which is (ammine)(glycolato-O,O')(piperidine)platinum (II).
Dependencies are inferred from the claim text.