Process for making lipid films suitable for liposomes
AssigneeCiba Corning Diagnostics Corp.
InventorSay-Jong Law
Life of this patent
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Abstract
A method for forming lipid films having a substantially uniform thickness and a ratio of the surface area of deposited film to lipid concentration of less than 600 cm.sup.2 per mmole. Using a substantially flat stationary surface for lipid depositation and evaporation results in the formation of lipid films suitable for commercial production of liposomes.
Claims3
A process for forming lipid films of a substantially uniform thickness, having a surface area of deposit to lipid concentration ratio of less than 600 cm.sup.2 /mmole, comprising depositing a lipid solution in a stationary vessel having a substantially level horizontal surface, then evaporating the liquid so as to form a lipid film while maintaining the vessel in a stationary horizontal position.
A process for forming liposomes by hydration of a lipid film comprising adding a liquid to a lipid film made by depositing a lipid solution in a stationary vessel having a substantially level horizontal surface, then evaporating the liquid so as to form a lipid film while maintaining the vessel in a stationary horizontal position.
Dependencies are inferred from the claim text.