Process for the catalytic animation of alcohols and diols using non-acidic hydroxyapatite catalysts
AssigneeAir Products and Chemicals, Inc.
InventorsGene E. Parris, Ronald Pierantozzi
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Abstract
The present invention relates to a process for the catalytic amination of 1.degree. and 2.degree. alcohols and diols wherein an amine is reacted with an alcohol or diol in the presence of a non-acidic cationic hydroxyapatite catalyst. A typical reaction includes the amination of ethanol with piperidine to form N-ethylpiperidine. The hydroxyapatite catalyst provides high conversion and selectivity toward the N-alkylated product. Product selectivity can be controlled by adjusting the ratio of cation to phosphorus in the hydroxyapatite catalyst.
Claims13
A process for the catalytic amination of a 1.degree. or 2.degree. alcohol or diol with a 1.degree. or 2.degree. amine which comprises passing a mixture of the amine and the alcohol or diol at an elevated temperature over a catalyst comprising a non-acidic cationic hydroxyapatite.
A process for the catalytic amination of a 1.degree. or 2.degree. alcohol or diol with a 1.degree. or 2.degree. amine which comprises passing a mixture of the amine and the alcohol or diol at an elevated temperature over a catalyst comprising a non-acidic cationic hydroxyapatite represented by the formula:
- ##STR5## wherein M.sup.a is a cation selected from the group consisting of Ca.sup.2+, Mg.sup.2+, Sr.sup.2+, La.sup.3+, Ce.sup.3+, Fe.sup.2+, Cu.sup.2+, Zn.sup.2+, Al.sup.3+, B.sup.3+ and Ga.sup.3+ and wherein the cation to phosphorus ratio, x/y, ranges from about 1.3 to about 2.4, calculated when a is 2.sup.+ and from about 0.87 to about 1.6 when a is 3.sup.+ and the ratio of z/y is about 1 to 3.
A process for the catalytic amination of a 1.degree. or 2.degree. alcohol or diol with a 1.degree. or 2.degree. amine which comprises passing a mixture of the amine and the alcohol or diol at an elevated temperature over a catalyst comprising a non-acidic cationic hydroxyapatite represented by the formula:
- ##STR6## wherein the cation to phosphorus ratio, x/y, is from about 1.67 to about 2.4 and the ratio of z/y is about 0.33 to about 1.79.
Dependencies are inferred from the claim text.