4H-1-benzopyran-4-one compounds which have anti-inflamatory or immunodulating action

A compound of the formula I ##STR13## in which:

• R.sub.1 is hydrogen, unsubstituted C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.6 alkyl substituted by halogen, hydroxy or carboxy, phenyl-C.sub.1 -C.sub.4 -alkyl wherein the phenyl is unsubstituted or mono- or polysubstituted by halogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, nitro or trifluoromethyl, C.sub.3 -C.sub.6 -cycloalkyl, C.sub.3 -C.sub.6 -cycloalkyl-C.sub.1 -C.sub.4 -alkyl, C.sub.2 -C.sub.6 -alkenyl, C.sub.3 -C.sub.6 -alkynyl, phenyl which is unsubstituted or mono- or polysubstituted by halogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, nitro, trifluoromethyl, amino or hydroxy, or is carboxyl, an aldehyde or -COO-C.sub.1 -C.sub.4 -alkyl group, or 2- or 4-pyridyl,
• R.sub.2 is hydrogen, C.sub.1 -C.sub.6 -alkyl, nitro, amino, di-C.sub.1 -C.sub.4 -alkylamino or di-C.sub.1 -C.sub.4 -alkylaminomethyl or a halogen atom,
• R.sub.3 is unsubstituted C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkyl substituted by halogen, hydroxy or carboxy, hydroxyl, C.sub.1 -C.sub.4 -alkoxy, phenyl-C.sub.1 -C.sub.4 -alkyl wherein the phenyl is unsubstituted or mono- or polysubstituted by halogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, nitro or trifluoromethyl, nitro, halogen, amino, C.sub.1 -C.sub.4 -alkylamino or di-C.sub.1 -C.sub.4 -alkylamino,
• R.sub.4 is hydrogen, hydroxyl, C.sub.1 -C.sub.4 -alkoxy, C.sub.1 -C.sub.4 -alkanoyloxy, C.sub.1 -C.sub.4 -alkoxycarbonyl, phenoxy which is unsubstituted or mono- or polysubstituted by halogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, nitro or trifluoromethyl, amino, C.sub.1 -C.sub.4 -alkylamino or di-(C.sub.1 -C.sub.4 -alkyl)-amino,
• R.sub.5 is hydrogen, unsubstituted C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.6 -alkyl substituted by halogen, hydroxy or carboxy, phenyl-C.sub.1 -C.sub.4 -alkyl wherein the phenyl is unsubstituted or mono- or polysubstituted by halogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, nitro or trifluoromethyl, C.sub.3 -C.sub.6 -cycloalkyl, C.sub.3 -C.sub.6 -cycloalkyl-C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkanoyl or phenylcarbonyl which is unsubstituted or mono- or polysubstituted by halogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, nitro or trifluoromethyl,
• n is an integer between 0 and 2 and
• m is an integer between 0 and 3,
• with the exception of the compound 5,7-dihydroxy-2-methyl-8-[4'-(3'-hydroxy-1'-methyl)-piperidinyl]-4H-1-benz opyran-4-one,
• or a pharmacologically acceptable acid addition salt or optical isomer thereof.