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US 4,899,758 AGranted
Method and apparatus for monitoring and diagnosing hypertension and congestive heart failure
AssigneeRegents of the University of Minnesota
InventorsStanley M. Finkelstein, Jay N. Cohn
Life of this patent
Estimating the term…
Abstract
Apparatus and method for monitoring and diagnosing CHF and hypertension includes digitizing brachial artery pulses and determining C.sub.2 from modified Windkessel model. CHF and hypertension are monitored and diagnosed by tracking C.sub.2 values and testing values against a disease discriminating threshold of 0.08 ml/mm Hg.
Claims15
A congestive heart failure monitor comprising:
- RAM means for storing data;
- input means for receiving and storing a cardiac output
- transducer means for converting an arterial pressure to a corresponding electrical analog signal;
- analog to digital converter means for receiving said analog signal and digitizing it at a predetermined sampling rate;
- means for storing digitized samples produced by said converter means in said RAM means, said samples being stored over a time interval so that one or more pressure waves, each corresponding to a beat of the human heart, are digitized and stored in said RAM means as a series data bytes, each byte representing the instantaneous pressure of the arterial pressure;
- means for determining a mean arterial pressure value from said stored data bytes and storing said value;
- means for determining the value of the parameter C.sub.2 of the modified Windkessel model from the pulse contour of the diastolic portion of said waves and from said stored mean arterial pressure value and said stored cardiac output value;
- means for testing said C.sub.2 value against a predetermined threshold value of approximately 0.07 ml/mm Hg indicative of a congestive heart failure condition and identifying a congestive heart failure condition for C.sub.2 values below said threshold;
- and
- means for indicating said identified condition to a user of said vascular compliance monitor.
7 more elements
A congestive heart failure monitor comprising:
- RAM means for storing data;
- input means for receiving and storing a cardiac output value;
- transducer means for converting an arterial pressure to a corresponding electrical analog signal;
- analog to digital converter means for receiving said analog signal and digitizing it at a predetermined sampling rate;
- means for storing digitized samples produced by said converter means in said RAM means, said samples being stored over a time interval so that one or more pressure waves, each corresponding to a beat of the human heart, are digitized and stored in said RAM means as a series of data bytes, each byte representing the instantaneous pressure of the arterial pressure;
- means for determining a mean arterial pressure value from said stored data bytes and storing said value;
- means for determining the value of the parameter C.sub.2 of the modified Windkessel model from the pulse contour of the diastolic portion of said waves and from said stored mean arterial pressure value and cardiac output value;
- means for storing a plurality of C.sub.2 values from a plurality of individual determinations done at successive times by said means for determining whereby a plurality of C.sub.2 values may be accumulated over a period of time;
- means for determining the slope of said stored accumulated C.sub.2 values over time;
- means for inspecting said slope and determining if said accumulated C.sub.2 values are trending upward or downward and identifying a deteriorating CHF condition if said slope is negative and identifying an improving CHF condition if said slope is positive;
- and
- means for indicating the identified improving or deteriorating condition to the user of said monitor whereby congestive heart failure may be monitored.
9 more elements
A method of diagnosing congestive heart failure, comprising the steps of:
- (a) obtaining a cardiac output value;
- (b) measuring arterial pressure using a transducer, said transducer producing an electrical analog signal corresponding to said arterial pressure;
- (c) sampling said analog signal over time at a predetermined sampling rate to provide a series of values representing one or more pressure waves each corresponding to a beat of the human heart;
- (d) determining the mean arterial pressure from said series of values;
- (e) determining the value of the parameter C.sub.2 of the modified Windkessel model from the pulse contour of the diastolic portion of said one or more waves as represented by said series of values and from said mean arterial pressure and cardiac output value;
- and
- (f) testing said C.sub.2 value against a predetermined threshold value below which C.sub.2 values are associated with a congestive heart failure condition whereby a CHF condition may be identified.
4 more elements
A method for monitoring congestive heart failure, comprising the steps of:
- (a) obtaining a cardiac output value;
- (b) measuring an arterial pressure using a transducer, said transducer producing an electrical analog signal corresponding to said arterial pressure;
- (c) sampling said analog signal over time at a predetermined sampling rate to provide a series of values representing one or more pressure waves each corresponding to a beat of the human heart;
- (d) determining the mean arterial pressure from said series of values;
- (e) determining the value of the parameter C.sub.2 of the modified Windkessel model from the pulse contour of the diastolic portion of said one or more waves as represented by said series of values and from said mean arterial pressure and cardiac output value;
- (f) recording said determining C.sub.2 value;
- (g) repeating steps (a) through (f) at successive times to accumulate a plurality of recorded C.sub.2 values over a period of time;
- (h) comparing the first of said accumulated C.sub.2 values against a predetermined diagnostic threshold value discriminating between C.sub.2 values associated with a healthy condition;
- (i) identifying an improving congestive heart failure condition when said first C.sub.2 value is below said threshold value and the remaining C.sub.2 values are trending toward said threshold value;
- (j) identifying an improving healthy trend away from a congestive heart failure condition when said first C.sub.2 value is above said threshold value and the remaining C.sub.2 values are trending away from said threshold value;
- (k) identifying a deteriorating congestive heart failure condition when said first C.sub.2 value is below said threshold value and the remaining C.sub.2 values are trending away from said threshold value;
- and
- (1) identifying a trend toward a congestive heart failure condition when said first C.sub.2 value is above said threshold value and the remaining C.sub.2 values are trending toward said threshold value.
10 more elements
A method of diagnosing congestive heart failure, comprising the steps of:
- (a) obtaining a cardiac output value;
- (b) measuring arterial pressure over time to obtain a representation of one or more pressure waves each corresponding to a beat of the human heart;
- (c) determining the mean arterial pressure;
- (d) determining the value of the parameter C.sub.2 of the modified Windkessel model from the pulse contour of the diastolic portion of said one or more waves and from said mean arterial pressure and cardiac output value;
- and
- (e) testing said C.sub.2 value against a predetermined diagnostic threshold value below which C.sub.2 values are associated with a congestive heart failure condition whereby a CHF condition may be identified.
3 more elements
A method for monitoring congestive heart failure, comprising the steps of:
- (a) obtaining a cardiac output value;
- (b) measuring arterial pressure over time to obtain a representation of one or more pressure waves each corresponding to a beat of the human heart;
- (c) determining the mean arterial pressure;
- (d) determining the value of the parameter C.sub.2 of the modified Windkessel model from the pulse contour of the diastolic portion of said one or more waves and from said mean arterial pressure and cardiac output value;
- (e) recording said determined C.sub.2 value;
- (f) repeating steps (a) through (e) at successive times to accumulate a plurality of recorded C.sub.2 values over a period of time;
- (g) comparing the first of said accumulated C.sub.2 values against a predetermined diagnostic threshold value discriminating between C.sub.2 values associated with a congestive heart failure condition and those C.sub.2 values associated with a healthy condition;
- (h) identifying an improving congestive heart failure condition when said first C.sub.2 value is below said threshold value and the remaining C.sub.2 values are trending toward said threshold value;
- and
- (i) identifying an improving healthy trend away from a congestive heart failure condition when said first C.sub.2 value is above said threshold value and the remaining C.sub.2 values are trending away from said threshold value;
- (j) identifying a deteriorating congestive heart failure condition when said first C.sub.2 values is below said threshold value and the remaining C.sub.2 values are trending away from said threshold value;
- and
- (k) identifying a trend toward a congestive heart failure condition when said first C.sub.2 value is above said threshold value and the remaining C.sub.2 values are trending toward said threshold value.
10 more elements
Dependencies are inferred from the claim text.