Antiviral compositions
AssigneeYeda Research and Development Co. Ltd.
InventorsDavid Lavie, Michel Revel, Dalia Rotman, Vincent V. Velde
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Abstract
The invention relates to antiviral compositions of matter containing as active ingredient hypericin or pseudohypericin. The novel compositions are of special use in the treatment of, and alleviation of symptoms of various diseases caused by viruses such as vesicular stomatitis, influenza, herpes simplex, HSV-1 and HSV-2. The mode of activity seems to be by inhibition of RNA synthesis and interfering with virus replication. The pharmaceutical compositions can be applied by a variety of routes. Topical applications have proved to be effective against a variety of viral afflictions.
Claims16
A topical antiviral pharmaceutical composition comprising, a pharmaceutically acceptable excipient suitable to place the composition into form for topical administration and, as active ingredient, an antiviral effective quantity of a pure compound selected from the group consisting of hypericin, pseudohypericin, a pharmaceutically acceptable salt of hypericin or pseudohypericin, and mixtures thereof in any desired ratio.
A method of treating vial infections in a mammal afflicted with a viral infection, comprising administering to said mammal an effective antiviral amount of a substantially pure compound selected from the group consisting of hypericin, pseudohypericin, a pharmaceutically acceptable salt of hypericin or pseudohypericin, and mixtures thereof in any desired ratio.
Dependencies are inferred from the claim text.