17-Hydroxy-steroids
OwnerArthur G. Schwartz, Marvin L. Lewbartinventors
Life of this patent
Estimating the term…
Abstract
Compounds of the formulae: ##STR1## are useful as anti-cancer, anti-obesity, anti-diabetic, anti-coronary agents, anti-aging agents, anti-hypolipidemic agents and anti-autoimmune agents.
Claims101
Compounds of the formulae:
- ##STR72## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.7, R.sub.8, R.sub.11, R.sub.12, R.sub.13, R.sub.14, R.sub.15, and R.sub.17 are each independently hydrogen, lower alkyl, halogen, or lower alkoxy;
- R.sub.5 and R.sub.6 are independently hydrogen, lower alkyl or lower alkoxy;
- R.sub.16 is lower alkyl, halogen, or lower alkoxy;
- R.sub.9 is hydrogen, lower alkyl or halogen;
- and
- R.sub.18 and R.sub.19 are each independently hydrogen, lower alkyl, lower alkenyl, lower alkynyl, formyl, lower alkanoyl or epoxy.
Compounds of the formulae:
- ##STR73## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.7, R.sub.8, R.sub.11, R.sub.12, R.sub.13, R.sub.14 (and) R.sub.15 and R.sub.17 are each independently hydrogen, lower alkyl, halogen, hydroxy, or lower alkoxy;
- and R.sub.5 and R.sub.6 are independently hydrogen, lower alkyl or lower alkoxy;
- R.sub.16 is lower alkyl, halogen, or lower alkoxy;
- R.sub.9 and R.sub.10 are independently hydrogen, lower alkyl or halogen;
- and
- R.sub.18 and R.sub.19 are each independently hydrogen, lower alkyl, lower alkenyl, lower alkynyl, formyl, lower alkanoyl or epoxy.
Compounds of the formulae:
- ##STR74## wherein R.sub.5 and R.sub.6 are independently hydrogen or lower alkyl;
- R.sub.16 is lower alkyl, halogen or lower alkoxy,
- R.sub.17 is hydrogen, lower alkyl, halogen, or lower alkoxy;
- and
- R.sub.18 and R.sub.19 are each independently hydrogen, lower alkyl, lower alkenyl, lower alkynyl, formyl, lower alkanoyl or epoxy.
Compounds of the formulae:
- ##STR75## wherein R.sub.5 and R.sub.6 are independently hydrogen or lower alkyl;
- R.sub.16 is lower alkyl, halogen or lower alkoxy;
- R.sub.17 is hydrogen, lower alkyl, halogen, hydroxy or lower alkoxy;
- and
- R.sub.18 and R.sub.19 are each independently hydrogen, lower alkyl, lower alkenyl, lower alkynyl, formyl, lower alkanoyl or epoxy.
The compound having the formula:
- ##STR80##
The compound having the formula:
- ##STR81##
The compound having the formula:
- ##STR82##
The compound having the formula:
- ##STR83##
The compound having the formula:
- ##STR84##
The compound having the formula:
- ##STR85##
The compound having the formula:
- ##STR86##
The compound having the formula:
- ##STR90##
The compound having the formula:
- ##STR91##
The compound having the formula:
- ##STR92##
The compound having the formula:
- ##STR93##
The compound having the formula:
- ##STR97##
The compound having the formula:
- ##STR98##
The compound having the formula:
- ##STR99##
The compound having the formula:
- ##STR100##
The compound having the formula:
- ##STR101##
The compound having the formula:
- ##STR102##
The compound having the formula:
- ##STR103##
The compound having the formula:
- ##STR107##
The compound having the formula:
- ##STR108##
The compound having the formula:
- ##STR109##
The compound having the formula:
- ##STR110##
The compound having the formula:
- ##STR111##
The compound having the formula:
- ##STR112##
The compound having the formula:
- ##STR113##
The compound having the formula:
- ##STR114##
The compound having the formula:
- ##STR117##
The compound which is:
- ##STR118##
The compound which is:
- ##STR119##
The compound which is:
- ##STR120##
Dependencies are inferred from the claim text.