Novel naphthalenylalkyl-3H-1,2,3,5-oxathiadiazole 2-oxides useful as antihyperglycemic agents
AssigneeAmerican Home Products Corporation
InventorsThomas R. Alessi, Terence M. Dolak, John W. Ellingboe, Louis J. Lombardo
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Abstract
This invention relates to novel [(substituted naphthalenyl)alkyl]-3H-1,2,3,5-oxathiadiazole 2-oxides, to the processes for their preparation, to methods for using the compounds, and to pharmaceutical compositions thereof. The compounds have pharmaceutical properties which render them beneficial for the treatment of diabetes mellitus and associated conditions.
Claims27
A compound of formula (I) ##STR17## wherein R.sup.1 and R.sup.` are independently hydrogen, lower alkyl containing 1 to 6 carbon atoms, alkoxy containing 1 to 6 carbon atoms, halogen, ethynyl, nitrile, methylthio, trifluoromethyl, vinyl, nitro or halogen substituted benzyloxy;
- or n is 0 to 4 or the pharmaceutically acceptable salts thereof.
Dependencies are inferred from the claim text.