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US 4,895,808 AGranted
Method and apparatus for adsorption detection
AssigneeRomer Labs, Inc.
InventorThomas R. Romer
Life of this patent
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AssigneeRomer Labs, Inc.
InventorThomas R. Romer
Estimating the term…
A method and apparatus for adsorption and detection of adsorbents or analytes. The method and apparatus can be employed in the field for rapid adsorption of analytes and is particularly useful for detection of mycotoxins. A sample to be analyzed is prepared in solution and placed in a test tube. A tube-like adsorption column having a seal and a valve member is forcefully fed into the test tube to force solutions through the valve member into the column and through a filter and adsorbent to trap interference. The semi-purified solution may then be analyzed for the presence of analytes. The column with the purified solution may be further employed with a second smaller adsorption column similarly equipped with a seal and valve member fitting within the first column. In similar fashion the second column may be forced into the first column to expel the solution therein into the second column and through one or more selective adsorbents for different analytes such as one or more mycotixins. Detection of the adsorbed analyte may be made by shining a fluorescent or "black" light on the adsorbent which fluoresces to indicate presence of the analyte.
A method for purification of analytes in a solution which comprises placing said solution in a test tube, inserting a pressure exerting adsorption column having a resilient seal closely engaging an inner wall of said test tube to force said solution into said column through a bottom opening in said column past a filter member and past an adsorbent packing material to adsorb interference material to provide semi-purified solution in which solid and soluble interferences are removed, withdrawing said semi-purified solution and subjecting said solution to a selective detection procedure for further analysis of analytes therein.
A method for purification of analytes in a solution which comprises placing said solution in a test tube, inserting a first pressure exerting adsorption column having a resilient seal closely engaging an inner wall of said test tube to force said solution into said first column through a bottom opening in said first column past a filter member and past an adsorbent packing material to adsorb interference material to provide a semi-purified solution and withdrawing said semi-purified solution for further analysis of analytes therein, said analytes in the semi-purified solution being detected by inserting a second pressure exerting adsorption column into said first column, said second column having a resilient seal closely engaging an inner wall of said first column to force said semi-purified solution into said second column through a bottom opening in said column past a selective adsorbent packing material having a selective adsorbent capacity for the analyte to be detected and testing said selective adsorbent for the presence of said analyte.
A method for purification of mycotoxin analytes in a solution containing at least one of feed grains and foodstuffs which comprises placing said solution in a test tube, inserting a pressure exerting adsorption column having a resilient seal closely engaging an inner wall of said test tube to force said solution into said column through a bottom opening in said column past a filter member and past an adsorbent packing material to adsorb interference material to provide a semi-purified solution in which solid and soluble interferences are removed, withdrawing said semi-purified solution and subjecting said solution to a selective detection procedure for further analysis of mycotoxin analytes therein.
Dependencies are inferred from the claim text.