Micropipettes and fabrication thereof
AssigneeActivational Systems, Inc.
InventorChris Chiodo
Life of this patent
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AssigneeActivational Systems, Inc.
InventorChris Chiodo
Estimating the term…
A novel method for fabricating glass micropipettes comprises assembling glass tubes side-by-side in a bundle, softening an axially central region of the bundle by heating, axially elongating the softened central region to create two opposing tapers, and then dividing the bundle in two at the axial midpoint of the central region to thereby create two micropipettes. The distal tip end of each micropipette at which it was separated from the other is then relatively advanced toward a hot flame to create a spherical enlargement at the tip end. This spherical enlargement facilitates subsequent gripping of this end when the micropipette is subsequently finished to produce desired orifice sizes for the barrels at the distal tip end. It is also desirable to perform a twisting step after the softening step and before the elongating step.
The method of making a pair of multiple barrel glass micropipettes comprising:
The method of making a pair of multiple barrel glass micropipettes comprising:
The method of making a pair of multiple barrel glass micropipettes comprising:
A multiple barrel glass micropipette comprising a bundle of individual glass tubes that are arranged axially side-by-side along at least a distal end portion of the bundle and are tapered to a tip in said distal end portion which is subsequently axially drawn to a desired size and said distal end portion of said tip is endowed with a bulbous shape that is radially enlarged in comparison to an immediately proximal portion of said tip but is radially smaller than the radial dimension of the bundle as measured across the axially side-by-side arranged portion thereof immediately proximal the taper.
Dependencies are inferred from the claim text.