Substituted basic 2-aminotetralin useful as cardiotonic agents
AssigneeBayer Aktiengesellschaft
InventorsRudolf Schohe, Thomas Glaser, Jorg Traber, George S. Allen
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Abstract
For treatment of disorders of the central nervous system, the cardiovascular system or the intestinal tract, the new substituted basic 2-aminotetralins of the formula ##STR1## in which R.sup.1 represents hydrogen or alkyl, R.sup.2 represents hydrogen, alkyl or acyl, and R.sup.3 represents quinuclidine or a group of the formula --(CH.sub.2).sub.a --R.sup.4, --CH.sub.2 --CH.dbd.CH--(CH.sub.2).sub.b --R.sup.4, --CH.sub.2 --C.tbd.(CH.sub.2).sub.b --R.sup.4, ##STR2## wherein a denotes a number from 1 to 10, b denotes a number 0, 1, 2, 3 or 4, d denotes a number 2 or 3, and X denotes oxygen, sulphur, or NR.sup.5, and their salts.
Claims10
A substituted basic 2-aminotetralin of the formula ##STR124## in which R.sup.1 represents hydrogen or alkyl,
- R.sup.2 represents hydrogen, alkyl or acyl, and
- R.sup.3 represents a group of the formula --(CH.sub.2).sub.a --R.sup.4, --CH.sub.2 --CH.dbd.CH--(CH.sub.2).sub.b --R.sup.4 or --CH.sub.2 --C.tbd.C--(CH.sub.2).sub.b --R.sup.4, ##STR125## wherein a denotes a number from 1 to 10, and
- b denotes a number 0, 1, 2, 3 or 4, and
- R.sup.4 denotes ##STR126## wherein n denotes a number 1 or 2, or its salt.
Dependencies are inferred from the claim text.