US 4,876,399 A · Taxols, their preparation and intermediates thereof

Abstract

The present invention is directed to novel taxols useful as a chemotherapeutic agent. Moreover, the present invention is directed to the process of preparing taxols and various intermediates in said process. A key intermediate is this process is 2,5-dihydroxy-2-patchoulenes. Therefore the present invention is also related to said intermediate and the process for its preparation.

Claims3

Dependent claims

A diol of the formula:

##STR10##

Dependencies are inferred from the claim text.

Facts

Application

07/115,665Filed 2 Nov 1987

Granted

24 Oct 1989

Term ends

Not estimatedThe source records don’t support an estimate.

Classification9 codes

C07C 233/47
With the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom: having the carbon atom of…
C07C 35/37
Polycyclic, at least one hydroxy group bound to a condensed ring system: with a hydroxy group on a condensed system having three rings
C07C 233/49
With the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom: having the carbon atom of…
C07C 233/87
With the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom: of a carbon skeleton…

Taxols, their preparation and intermediates thereof

Life of this patent

Abstract

Claims3

Taxols, their preparation and intermediates thereof

Life of this patent

Abstract

Claims3