Method for reducing viral transmission with poly-L-histidine
AssigneeThe Research Foundation of State University of New York
InventorsJerry J. Pollock, John J. Docherty
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Abstract
A composition for reducing the transmissability of viral infection from a subject infected therewith which comprises a topically applicable, pharmaceutically acceptable carrier and a viricidally effective amount of a polypeptide of between 24 and 500 aminoacid residues comprising at least 24 residues of L-Histidine.
Claims13
A method for reducing the transmissability of Herpes viral infection from a subject infected therewith which comprises topically adminstering a viricidally effective amount of poly-L-Histidine of between 24 and 500 amino acid residues, at a pH of less than 7 to a subject in need of same.
A method for reducing the transmissability of a Herpes viral infection from a first subject infected therewith to a second subject in contact with said first subject which comprises topically applying viricidally an effective amount of poly-L-Histidine of between 24 and 500 amino acid residues, at a pH of less than 7 to tissues of said first subject, at or proximate to the location of tissue lesions caused by said infection.
A method for reducing the transmissability of a Herpes viral infection from a subject infected therewith to a second subject in contact with said first subject which comprises topically applying a poly-L-Histidine of between 24 and 500 amino acid residues, at a pH of less than 7 to tissues of said second subject, at or proximate to a location likely to come into contact with the location of tissues of said first subject likely to have lesions caused by said infection.
A method for reducing the transmissability of a Herpes viral infection in a subject infected therewith to a different tissue location on said subject which comprises topically applying viricidally an effective amount of a poly-L-Histidine of between 24 and 500 amino acid residues comprising at least 24 residues of L-Histidine, at a pH of less than 7 to tissues of said subject, at or proximate to a location on said subject likely to have lesions caused by said infection.
Dependencies are inferred from the claim text.