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AssigneesMission Pharmacal Company, Board of Regents, The University of Texas System
InventorsCharles Y. C. Pak, Neill B. Walsdorf
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The present invention comprises a composition of matter consisting essentially of citric acid and one or more calcium compounds selected from the group consisting of calcium hydroxide, calcium carbonate and calcium oxide. The composition of matter is preferably a substantially dry mixture which may be used, for example, as a powder for making an "instant" beverage of potable liquid. A preferred calcium compound/citric acid molar ratio in the composition of matter of the present invention is between about 0.6 and about 1.5. In a most preferred embodiment, the composition of matter of the present invention consists essentially of calcium hydroxide and citric acid having a calcium compound/citric acid or calcium hydroxide/citric acid molar ratio of about 1.25. The composition of matter of the present invention has a utility demostrated by dissolution in water to form a liquid dietary calcium supplement comprising soluble calcium citrate. This composition of matter may comprise one or more of a flavorant, lubricant, sweetener or colorant usable to maintain a powdery texture or to enhance the flavor of a beverage prepared therefrom.
A composition of matter consisting essentially of calcium hydroxide and citric acid in a calcium hydroxide/citric acid molar ratio between about 0.6 and about 3.0.
A composition of matter for dissolution in water to form a liquid dietary calcium supplement comprising soluble calcium citrate, the composition of matter being substantially dry and consisting essentially of citric acid and a calcium compound selected from the group consisting of calcium hydroxide, calcium carbonate and calcium oxide, the composition of matter being further characterized in that the calcium compound and citric acid are in a calcium compound/citric acid molar ratio between about 0.6 and about 3.0.
A soluble calcium dietary supplement consisting of a dry premix of calcium carbonate and citric acid in a molar ratio in the range of about 0.67 to about 1.25.
A pharmaceutical composition for the dietary calcium supplementation of a subject, the composition comprising a mixture of calcium hydroxide and citric acid in a calcium hydroxide/citric acid molar ratio of between about 0.67 and 1.25
A potable liquid suitable for dietary supplementation of calcium without substantial risk of calcium renal stone facilitation or enhancement the preparation consisting essentially of:
A method for preparing a mixture, said mixture being soluble in an aqueous solvent to form a potable liquid consisting essentially of calcium citrate, the method comprising mixing calcium hydroxide and citric acid a calcium hydroxide/citric acid molar ratio of between about 0.6 and about 3.0.
A method for preparing a potable liquid consisitng essentially of calcium citrate and citric acid, the method comprising:
A method of preparing a pharmaceutical composition for dietary calcium supplementation of a subject comprising the steps of:
A method for supplementing dietary calcium comprising administration of a mixture of calcium hydroxide and citric acid in a calcium hydroxide/citric acid molar ratio of between about 0.67 and about 1.5.
A method for supplementing dietary calcium comprising:
Dependencies are inferred from the claim text.